MAGEA1 (Center) Peptide
产品名称： MAGEA1 (Center) Peptide
英文名称： MAGEA1 (Center) Peptide
产品编号： P1771
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MAGEA1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human MAGEA1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The MAGE-A1 gene expression is not determined solely by methylation status of the promoter region in hematological malignancies.
Suyama T, Ohashi H, Nagai H, Hatano S, Asano H, Murate T, Saito H, Kinoshita T.Leuk Res. 2002 Dec;26(12):1113-8.
- 2.
- Comparative genome sequence analysis of the Bpa/Str region in mouse and Man.
Mallon AM, Platzer M, Bate R, Gloeckner G, Botcherby MR, Nordsiek G, Strivens MA, Kioschis P, Dangel A, Cunningham D, Straw RN, Weston P, Gilbert M, Fernando S, Goodall K, Hunter G, Greystrong JS, Clarke D, Kimberley C, Goerdes M, Blechschmidt K, Rump A, Hinzmann B, Mundy CR, Miller W, Poustka A, Herman GE, Rhodes M, Denny P, Rosenthal A, Brown SD.Genome Res. 2000 Jun;10(6):758-75.
- 3.
- The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28.
Rogner UC, Wilke K, Steck E, Korn B, Poustka A.Genomics. 1995 Oct 10;29(3):725-31.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of MAGEA1 polyclonal antibody (Cat # PAB1980) in HeLa cell line lysates (35 ug/lane). MAGEA1 (arrow) was detected using the purified polyclonal antibody (1 : 60dilution).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human breast cancer tissue reacted with MAGEA1 polyclonal antibody (Cat # PAB1980) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with MAGEA1 polyclonal antibody (Cat # PAB1980) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 4100
- Protein Accession#:
- NP_004979
- Gene Name:
- MAGEA1
- Gene Alias:
- MAGE1,MGC9326
- Gene Description:
- melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
- Omim ID:
- 300016
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq
- Other Designations:
- OTTHUMP00000025911,melanoma antigen MAGE-1,melanoma antigen family A 1,melanoma antigen family A, 1,melanoma-associated antigen 1,melanoma-associated antigen MZ2-E