BLNK purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： BLNK purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： BLNK purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00029760-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human BLNK protein.
- Immunogen:
- BLNK (AAH18906.1, 1 a.a. ~ 456 a.a) full-length human protein.
- Sequence:
- MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEQQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS
- Host:
- Rabbit
- Reactivity:
- Human, Rat
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- BLNK MaxPab rabbit polyclonal antibody. Western Blot analysis of BLNK expression in PC-12.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of BLNK expression in transfected 293T cell line (H00029760-T03) by BLNK MaxPab polyclonal antibody.
Lane 1: BLNK transfected lysate(50.50 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 29760
- GeneBank Accession#:
- BC018906
- Protein Accession#:
- AAH18906.1
- Gene Name:
- BLNK
- Gene Alias:
- BASH,BLNK-S,LY57,MGC111051,SLP-65,SLP65
- Gene Description:
- B-cell linker
- Omim ID:
- 604515
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- B cell linker protein,B-cell adapter containing a SH2 domain protein,B-cell adapter containing a Src homology 2 domain protein,OTTHUMP00000020167,Src homology 2 domain-containing leukocyte protein of 65 kDa
- Interactome
- Related Disease